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Our Research - Microfluidics and Microplumbing
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"It’s kind of like plumbing; we’re
moving fluids around and dealing with different
pressures and flows. Only we’re doing it on a
microchip, as opposed to a house,” [Link]
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Opening: SMALL is looking for
students.
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Ph.D.
student who
wants to join my research group from Fall
2024.
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UB senior undergraduate
who wants to join
my research group from Spring 2024 AND
continue to
study in UB EE's PhD program under Prof. Oh's guidance from Fall 2024.
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June 2024
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Conference Chair: "Micro & Bio
Fluidics, Lab-on-Chip" at NanoTech 2024,
Washington DC, June 17-19, 2024 [Link]
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February 2024
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Publication: Philip J. Schneider,
Liam B. Christie, Nicholas M. Eadie, Tyler J. Siskar,
Viktor Sukhotskiy, Domin Koh, Anyang Wang, and Kwang W.
Oh,"Pysanky to Microfluidics: An Innovative Wax-Based
Approach to Low Cost, Rapid Prototyping of Microfluidic
Devices," Micromachines, 15(2), 240. [Link]
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January 2024
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New SMALL Member:
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Emamul Kabir (Spring 2024-)
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December 2023
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PhD Defense: Congratulations to Dr.
Liam Christie (MS, EE, UB, 2021; BS, EE,
UB, 2020). He has successfully defended his doctoral thesis
dissertation, "Study of Test Phantoms for Medical
Photoacoustic and Optical Imaging Applications," on
12/12/2023.
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August 2023
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Publication:
Christie LB, Zheng W, Johnson W,
Marecki EK, Heidrich J, Xia J, Oh KW, "Review of
imaging test phantoms," J Biomed Opt. 2023 Aug;
28(8): 080903. doi: 10.1117/1.JBO.28.8.080903. Epub 2023
Aug 22. PMID: 37614568; PMCID: PMC10442662. [Link]
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Course Offering: The course "EE 426/526
Wearable and Implantable Sensors" has a total of 73
students enrolled for the Fall of 2023. [Link]
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New SMALL Member:
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Ben Germaine (SMALL Member: Fall 2023-)
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June 2023
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Conference Chair: "Micro & Bio
Fluidics, Lab-on-Chip" at NanoTech 2023,
Washington DC, June 19-21, 2023 [Link]
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April 2023
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Mr.
Will Johnson is
one of fifteen UB students receiving a
2023 recipient of the SUNY Chancellor’s Award for
Student Excellence. [Link]
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March 2023
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MS Defense: Congratulations to Mr.
Will Giegerich (MS, EE, UB, 2023; BS, EE,
UB, 2022). He has successfully defended his MS thesis
dissertation, "Improving Vehicle Inspection and
Assessment using Classical Computer Vision and Machine
Learning Algorithms," on 3/29/2023.
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January 2023
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New SMALL Member:
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Jack Bakleh (SMALL Member: Spring 2023-)
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August 2022
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Buffalo Engineer 2022: Our SMALL
members, Phil Schneider (2014 - current), Dennis
Fedorishin (2017 - 2020), and William Giegerich (2020 -
current), working at ACV are featured in Buffalo
Engineer 2022 Magazine. See above images [Link]
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June 2022
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Conference Chair: "Micro & Bio
Fluidics, Lab-on-Chip" at NanoTech 2022,
Washington DC, June 13-15, 2022 [Link]
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February 2022
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Liam Christie is one of eight UB
students receiving SUNY GREAT awards [Link]
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January 2022
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New SMALL Member:
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Eric Merecki (SMALL Member: Spring 2022-)
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December 2021
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MS Defense: Congratulations to Mr.
Liam Chrstie (MS, EE, UB, 2021; BS, EE,
UB, 2020). He has successfully defended his MS
thesis dissertation, "Development of Optically,
Ultrasonically, and Mechanically Equivalent Test
Phantoms For Photoacoustic Applications," on 12/14/2021.
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October 2021
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Conference Chair: "Micro & Bio
Fluidics, Lab-on-Chip" at NanoTech 2021,
Washington DC, October 18-20, 2021 [Link]
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June 2021
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New SMALL Member:
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James Heidrich (SMALL Member: Summer 2021-)
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April 2021
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Oh has recieved Qualcomm Faculty Award.
[Link]
[Link]
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April 2021
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Publication:
Anyang Wang, Samaneh M. Boroujeni, Philip J. Schneider,
Liam B. Christie, Kyle A. Mancuso, Stelios T. Andreadis, Kwang W.
Oh, 2021. "An
Integrated Centrifugal Degassed PDMS-Based Microfluidic
Device for Serial Dilution" Micromachines 12, no. 5:
482. [Link]
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New SMALL Member:
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Noah Wichlacz (SHIP/Under: Spring
2021-): BS (EE, UB, Expected in 2022)
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January 2021
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Prof. Kwang W. Oh will serve as
Director of Graduate Studies in Electrical
Engineering at UB. [Link]
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New SMALL Member:
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Christopher Navarro (SMALL Meber: Spring 2021-): BS+MS (EE, UB, Expected in 2021)
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October 2020
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Publication:
Anyang Wang, Samaneh Moghadasi Boroujeni, Stelios T.
Andreadis and Kwang W. Oh, "An
Integrated Centrifugal Degassed PDMS-Based Microfluidic
Device for Serial Dilution," pp. 713-714,
Proceeding of MicroTAS 2020 (24th International
Conference on Miniaturized Systems for Chemistry and
Life Sciences, October 4 - 9, 2020, Virtual) [Link]
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Award: Prof. Kwang W. Oh receives The
2020 SUNY Chancellor’s Award for
Excellence in Teaching, honoring those who consistently
demonstrate superb teaching at the undergraduate,
graduate or professional level. [Link]
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August 2020
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Course: Prof. Kwang W. Oh teaches
EE 426/526 Wearable and Implantable Sensors
in Fall 2020, with a synchronous remote option.
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May 2020
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Publication: Linfeng Xu, Anyang Wang,
Xiangpeng Li, and Kwang W. Oh, "Passive micropumping in
microfluidics for point-of-care testing,"
Biomicrofluidics 2020, 14, 031503 (IF: 2.531) [Link]
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Conference Chair: "Micro & Bio
Fluidics, Lab-on-Chip" at NanoTech 2021,
Austin, TX, June 14-16, 2021 [Link]
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PhD Defense: Congratulations to Dr.
Anyang Wang (PhD, EE, UB, 2020; MS, EE, Tohoku
University, Japan, 2014; BS, EE Tohoku University,
Japan, 2012). He has successfully/virtually defended his PhD
thesis dissertation on 05/11/2020 via WebEx
as a result of the COVID-19 pandemic.
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PhD Defense: Congratulations to Dr.
Nikhila Nyayapathi (PhD, EE/BME, UB, 2020; MS, EE,
UB, 2016; BE, EE, Birla Institute of Technology &
Science, UAE, 2011). She was under Dr. Jun Xia's
Optical & Ultrasonic Imaging Lab in BME and Dr. Kwang W. Oh's SMALL Lab
in EE for her PhD study. She has successfully/virtually defended her PhD
thesis dissertation on 05/12/2020 via Zoom as a result of the COVID-19 pandemic.
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April 2020
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Congratulations to Mr.
Liam Christie, a senior in our
lab. He is this year’s recipient of the SUNY Chancellor’s Awards for Student Excellence. He has been a recipient of the
WNY Prosperity Fellow
scholarship since 2018, and has also undertaken
internships in the Jacobs Institute and with Moog. He is
an active member in our SMALL lab since 2016. He will
join SMALL lab as a PhD student in 2020.
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Guest Editor: Kwang W. Oh,
"Biomedical Microfluidic Devices 2020", Micromachines
(IF: 2.426) [Link]
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Paper Publication: Kwang W. Oh,
"Microfluidic Devices for Biomedical Applications:
Biomedical Microfluidic Devices 2019,"
Micromachines 2020, 11(4), 370; https://doi.org/10.3390/mi11040370 (IF: 2.426) [Link]
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March 2020
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EE Ranking: According
to US News & World Report, our EE Department moved
to 58 (in 2020) from the last year's ranking of 62
(in 2019) [Linkk].
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Distance Learning: UB moving to
distance learning from 3/23/2020 due to the COVID-19
outbreak. In Spring 2020, Prof. Kwang W. Oh offers
EE 311 Electronic Devices & Circuits 2 (via
YouTube/UBLearns) and
EE 428/528 BioMEMS & Lab-on-chip (via
Panopto/UBLearns).
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January 2020
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New BS Students:
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Ibrahima Barry (SHIP/Under: Spring
2020): BS (EE, UB, 2020)
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William Johnson (SMALL Meber: Spring 2020 -
): BS (EE, UB, Expected in 2022)
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William Giegerich (SMALL Meber: Spring 2020
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Nicholas Norwood (SMALL Meber: Spring 2020
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MS Defense: Congratulations to Mr. Evan Breloff
(MS, EE, UB, 2020; BS, EE, UB, 2013). He has
successfully defended his MS thesis dissertation on
01/15/2020. He is now with Qualcomm in Buffalo.
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October 2019
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Prof. Kwang W. Oh has been selected as
a recipient of the 2019 President Emeritus and Mrs.
Meyerson Award for Distinguished Undergraduate Teaching
and Mentoring. [Link]
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September 2019
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COURSE OFFERING: [Fall 2019] EE 426/526
Wearable & Implantable Sensors.
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August 2019
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PAPER PUBLICATION:
Anyang Wang, Domin Koh, Philip Schneider, Evan Breloff,
and Kwang W. Oh*, "A Compact, Syringe-Assisted,
Vacuum-Driven Micropumping Device," Micromachines 2019,
10(8), 543, https://doi.org/10.3390/mi10080543 (IF: 2.426) [Link]
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PAPER PUBLICATION:
Nikhila Nyayapathi,
Rachel Lim, Huijuan Zhang, Wenhan Zheng, Yuehang Wang,
Melinda Tiao, Kwang W. Oh, X. Cynthia Fan, Ermelinda
Bonaccio, Kazuaki Takabe, Jun Xia*, "Dual Scan
Mammoscope (DSM) – A New Portable Photoacoustic Breast
Imaging System with Scanning in Craniocaudal Plane,"
IEEE Transactions on Biomedical Engineering, DOI:
10.1109/TBME.2019.2936088 (IF: 4.491) [Link]
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June 2019
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Visiting Scholar: Mr. Hyun Jin Yoo (PhD
Candidate in Department of Integrative Engineering at
Chung-Ang University, South Korea) will work in SMALL
from June 2019 to September 2019.
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CONFERENCE CHAIR:
"Micro
& Bio Fluidics, Lab-on-Chip" at NanoTech 2019,
Boston, June 16-19, 2019.
Symposium Chair
Micro-, and bio-fluidics are highly interdisciplinary
fields that involve the study and control of transport
processes and related physical and chemical phenomena,
typically across multiple length and time scales and
also within the human body and biological tissue down to
the subcellular level. These fields are advancing
rapidly and applications are proliferating, especially
in the life sciences and biotechnology. The applications
of these fields are broad and encompass a diverse range
of areas that include micro total analysis systems
(MicroTAS), lab-on-a-chip (LOC) technology,
point-of-care (POC) clinical diagnostics,
organs-on-chip, drug discovery and delivery, on-chip
sensors, high-throughput systems, methods for
computational fluid dynamics, nanofluids and many
others. The aim of this symposium is to provide a forum
to discuss fundamental phenomena and advances in these
fields, associated technologies and current and emerging
commercial applications.
CONFIRMED INVITED TALKS:
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Mehmet Toner:
Harvard Medical School &
Massachusetts General Hospital
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Rohit Karnik:
MIT
Siddharatha Das: University of
Maryland College Park
Junhong Min: Chung-Ang University, South Korea
Leslie Yeo: RMIT University, Australia
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February 2019
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Prof. Kwang W. Oh has been awarded a
2019 Qualcomm Faculty Award (QFA) for
research that “inspires students and sparks new
approaches in key technology areas.” Related UBNow News:
"UB engineer receives Qualcomm Faculty Award" [Link]
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January 2019
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Ph.D DEFENSE: Congratulations to
Dr. Domin Koh (PhD, EE,
UB, 2019; BS, EE, UB, 2013). He has
successfully defended his Ph.D. thesis dissertation on
01/14/2019.
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November 2018
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CONFERENCE PAPERS/PRESENTATIONS:
- Anyang
Wang, Domin Koh, Phil Schneider and Kwang W. Oh, "A
compact syringe-assisted vacuum-driven micropumping
with a constant flow rate," Proceedings of MicroTAS
2018,
11-15 November, 2018,
Kaohsiung, Taiwan.
- Philip J.
Schneider, Liam Christie, Anyang Wang, Domin Koh,
and Kwang W. Oh, "Technology innovations in 3-D wax
based microfluidic device fabrication," Proceedings
of MicroTAS 2018,11-15 November, 2018,
Kaohsiung, Taiwan.
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September 2018
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PAPER PUBLICATION:
Kangsun Lee,* Choong
Kim and Kwang W. Oh,
"Single-Layered Microfluidic Network Based Combinatorial
Dilution for Standard Simplex Lattice Design,"
Micromachines 2018, 9(10), 489;
https://doi.org/10.3390/mi9100489 (IF: 2.222) [Link]
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PAPER PUBLICATION:
Yuehang Wang, Rachel
Su Ann Lim, Huijuan Zhang,
Nikhila Nyayapathi, Kwang W. Oh
& Jun Xia*, "Optimizing the light delivery of
linear-array-based photoacoustic systems by double
acoustic reflector," Scientific Reports, volume 8,
Article number: 13004 (2018) (IF: 4.122) ; [Link]
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Prof. Oh's Fall 2018 Course(s): EE 428/528 BioMEMS and
Lab-on-a-chip [Link]
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Prof. Oh/SMALL has been featured in Buffalo Engineer
Magazine 2018 [Link]
[PDF]:
BIG IDEAS ORIGINATING FROM SMALL
Kwang Oh is the director of the Sensors and
MicroActuators Learning Lab, known as SMALL, which
focuses on biomedical microfluidic devices, sensors
and actuators.
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July 2018
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Ph.D Defense: Congratulations to Dr. Philip Schneider (PhD, EE,
UB, 2018; MS, EE, UB, 2016; BS, EE, UB, 2014). He has
successfully defended his Ph.D. thesis dissertation on
07/09/2018. He is now with ACV.
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Accepted Abstracts: Two abstracts have been selected for
presentation in MicroTAS 2018,
Kaohsiung, Taiwan.
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June 2018
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PAPER PUBLICATION: Bendong Liu*,
Baohua Tian, Xu Yang, Mohan Li, Jiahui Yang, Desheng Li, and
Kwang W. Oh, "Manipulation of micro-objects
using acoustically oscillating bubbles based on the gas
permeability of PDMS," Biomicrofluidics 12, 034111 (2018);
https://doi.org/10.1063/1.5028419 (IF: 2.535) [Link]
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PAPER PUBLICATION: Yuehang Wang,
Zhengxiong Li, Tri Vu, Nikhila
Nyayapathi, Kwang W. Oh, Wenyao Xu and Jun
Xia*, "A Robust and Secure Palm Vessel Biometric Sensing System
based on Photoacoustics," IEEE Sensors Journal, DOI
10.1109/JSEN.2018.2843119, 2018 (IF: 2.512) [Link].
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May 2018.
[Image: Prof. Abe Lee from UC-Irvine
was one of invited speakers at this symposium.]
Anyang Wang, Domin Koh, Phil
Schneider, and Kwang W. Oh, "A compact syringe-assisted
vacuum-driven micropumping with a constant flow rate,"
Proceedings of NSTI Nanotech Confernce, Micro & Bio
Fluidics, Lab-on-Chip, NanoTech 2018, Vol. 3 Biotech,
Biomaterials and Biomedical: TechConnect Briefs 2018,
pp. 158-161, Anaheim, CA, May 13-16, 2018
CONFERENCE PROCEEDING:
P. Schneider, V. Sukhotskiy,
L. Christie, T. Siskar, I. H. Karampelas, E. P. Furlani,
and Kwang W. Oh, "Additive Manufacturing of Microfluidic
Components via Wax Extrusion," Proceedings of NSTI
Nanotech Confernce, Micro & Bio Fluidics, Lab-on-Chip,
NanoTech 2018, Vol. 3 Biotech, Biomaterials and
Biomedical: TechConnect Briefs 2018, pp. 162-165,
Anaheim, CA, May 13-16, 2018
CONFERENCE PROCEEDING:
P. Schneider, N. Eadie, L.
Christie, Y. Zhan, T. Siskar, D. Koh, J. Xia, and Kwang
W. Oh, "Microfluidic Test Target for Photoacoustic
Imaging," Proceedings of NSTI Nanotech Confernce, Micro
& Bio Fluidics, Lab-on-Chip, NanoTech 2018, Vol. 3
Biotech, Biomaterials and Biomedical: TechConnect Briefs
2018, pp. 166-169, Anaheim, CA, May 13-16, 2018
Prof. Oh
has also
attended NSF I/UCRC CITeR Spring 2018 Program Review (Atlanta,
GA).
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February 2018
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Kwang W. Oh, PhD, leads a team of researchers that
is bringing the concept of “lab on a chip” closer to
reality.
Researchers Help Bring Us Closer to Coin-Sized Medical
Labs
Published February
6, 2018
A team of researchers led by Kwang
W. Oh, PhD, associate professor of biomedical
engineering and electrical engineering, has
fabricated a chip that uses two different types of force
— capillary- and vacuum-driven — to manipulate how
fluids travel in micro- and nano-sized channels.
Medical Lab Could Fit on Chip the Size of Small Coin
The idea — shrinking a medical lab onto a chip the size
of a small coin — is known as “lab on a chip.” Using a
hand-held device, a practitioner would be able to draw
blood from a patient, and seconds later the device would
provide in-depth medical information about the patient.
It may sound like something from science fiction, but
it’s coming closer to reality. Obstacles still remain;
among them is finding an efficient and reliable way to
mix and move blood and other fluids through the chip’s
tiny valves and pumps.
A new study, appearing on the cover of the Jan. 21
edition of the journal Lab
on a Chip— which is published by the Royal Society
of Chemistry — moves the scientific community closer to
solving the problem.
Device Could Be Used on Battlefields, in the Home
The advancement solves a vexing issue, the researchers
say, because in such devices, when blood is mixed with a
reagent to produce a biological and/or chemical
reaction, the pressure difference between the two fluids
often causes them to flow backward instead of into the
desired channel.
“It’s kind of like plumbing; we’re moving fluids around
and dealing with different pressures and flows. Only
we’re doing it on a microchip, as opposed to a house,”
said Oh, the study’s lead author. “The chip could become
the basis for faster, more efficient and reliable lab on
a chip devices. It puts us closer to using such devices
where medical labs are lacking, such as the developing
world, battlefields and even our homes.”
Chip Requires No External Sources of Power
In a series of experiments, the research team showed how
its chip was able to accurately decipher the eight blood
types based upon the time it takes for different blood
types to flow through the chip. For example, when mixed
with a certain antibody, Type A blood will thicken and
flow slower.
Oh says the device could be used for other biological
and chemical assays. What’s more, the new chip requires
no sensors or external sources of power. That’s key for
medical device manufacturers, which are searching for
ways to inexpensively produce disposable lab on a chip
products.
His four co-authors are also associated with UB. Anyang
Wang, Domin Koh and Philip J. Schneider are doctoral
candidates in electrical engineering, while Yaguang Zhai
earned a master’s degree in electrical engineering in
2017.
The research was partially supported by grants from the National
Science Foundation Industry-University Cooperative
Research Centers Program and Qualcomm
Incorporated.
[Original
News Article from UB Medical School]
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January 2018
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1/26/18
Advancement in ‘microchip plumbing’ could aid developing
countries, soldiers and chronic disease sufferers.
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CONFERENCE
CHAIR: Prof. Oh will serve "The US-KOREA Conference on Science,
Technology and Entrepreneurship (UKC) 2018, August 1-4, 2018,
St. John’s University, Queens, New York, NY, USA", as a
sumposium cochair on Digital Technologies / Artificial
Intelligence Symposiums: Electrical, Electronics and
Communications (EEC) session. [Link]
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PAPER PUBLICATION/COVER PAGE:
Yaguang Zhai, Anyang Wang, Domin Koh, Philip Schneider and Kwang
W. Oh*, "A robust, portable and backflow-free micromixing device
based on both capillary- and vacuum-driven flows," Lab Chip,
2018, 18, 276-284; DOI: 10.1039/C7LC01077J (IF: 6.045). [Link]
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SMALL ANNOUNCEMENT FOR PREVIOUS YEARS (2017 - 2006) ...
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